A2B Adenosine Receptor and Cancer

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A2B Adenosine Receptor and Diabetic Erectile Dysfunction

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A2b adenosine receptor regulates hyperlipidemia and atherosclerosis.

BACKGROUND The cAMP-elevating A(2b) adenosine receptor (A(2b)AR) controls inflammation via its expression in bone marrow cells. METHODS AND RESULTS Atherosclerosis induced by a high-fat diet in apolipoprotein E-deficient mice was more pronounced in the absence of the A(2b)AR. Bone marrow transplantation experiments indicated that A(2b)AR bone marrow cell signals alone were not sufficient to e...

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Role of Adenosine receptor in lung cancer

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The A2b Adenosine Receptor Modulates Glucose Homeostasis and Obesity

BACKGROUND High fat diet and its induced changes in glucose homeostasis, inflammation and obesity continue to be an epidemic in developed countries. The A2b adenosine receptor (A2bAR) is known to regulate inflammation. We used a diet-induced obesity murine knockout model to investigate the role of this receptor in mediating metabolic homeostasis, and correlated our findings in obese patient sam...

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Vascular Medicine A2b Adenosine Receptor Regulates Hyperlipidemia and Atherosclerosis

Background—The cAMP-elevating A 2b adenosine receptor (A 2b AR) controls inflammation via its expression in bone marrow cells. Methods and Results—Atherosclerosis induced by a high-fat diet in apolipoprotein E– deficient mice was more pronounced in the absence of the A 2b AR. Bone marrow transplantation experiments indicated that A 2b AR bone marrow cell signals alone were not sufficient to eli...

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ژورنال

عنوان ژورنال: International Journal of Molecular Sciences

سال: 2019

ISSN: 1422-0067

DOI: 10.3390/ijms20205139